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Lipitor Market analysis and
forecasts Report, 2007-2012, 2017 &
2023
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Publication
Date
May 2008
Publisher
VISIONGAIN
Product Type
Report
Pages
not applicable
ISBN Number
not applicable
Product Code
VISG06
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Departmental copies
(this entitles up to 5
individual users in your
department
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In 2006, Pfizer’s
Lipitor (atorvastatin) generated global
revenues of $13.6bn, making it the best
selling drug in pharmaceutical history. The
blockbuster medicine has single-handedly
driven the overall revenue margins of the
cardiovascular segment, as this area
continues to dominate the pharmaceutical
market. Despite the maturing status of
Lipitor, the drug has repeatedly maintained
steady growth over the past 5 years,
crowding out the yearly revenues of other
lipid-regulating blockbuster drugs: Merck&
Co’s Zocor and Zetia, Astrazeneca’s Crestor,
Abbott’s Tricor and Bristol Myers Squibb’s
Pravacol.
However, as Lipitor’s blockbuster revenue is
seriously threatened by imminent patent
expiration in some of the drug’s largest
markets such as the US, Japan and the UK,
there is significant unrest between Pfizer’s
key stakeholders about the future of the
drug. Principally, amongst the heightened
Lipitor topics are the imminent exposure of
the $1 billion annual drug sales or more, as
well as the fast expanding generic market in
which India’s Ranbaxy is a dominant force.
What questions
does the report answer?
Has the success of Pfizer’s Lipitor been
overstated?
Did Pfizer create a monster in Lipitor?
Have Lipitor sales redefined the bounds that
pharmaceutical margins can now reach?
How imminent is Lipitor patent expiration?
Which key markets will suffer the
consequence of Lipitor expiry?
Is Ranbaxy ready for generic Lipitor?
Do the fast developing markets, CEE and the
Latin America segment hold the key to future
sales after Lipitor’s patent expiration?
Is Lipitor a victim of the struggling
Blockbuster Model?
What is next for
Lipitor?
Do the fast developing markets, CEE and
Latin America segment hold the key to future
sales after Lipitor’s patent expiration?
Is Lipitor, a victim of the struggling
Blockbuster Model?
What is next for Lipitor?
As Pfizer’s Lipitor
struggles to fend off the immediate entry of
Ranbaxy’s generic Lipitor, in key markets,
the legal challenges surrounding the number
one drug have set a new benchmark for
pharmaceutical companies protecting branded
products. Industry observers including
Visiongain predicts that Pfizer’s crises are
far from over, as the high revenue streams
of Lipitor will experience significant
challenges before the commencement of the
next decade.
Moreover, Pfizer’s lack of success to
replace Lipitor with Torcetrapib has
escalated the company’s near-term battles
besides the ever-tighter regulatory hurdles,
reduced R&D efficiency and increased
competition, creating formidable therapeutic
challenges as healthcare payers influence
pricing. Nevertheless, there are strong
drivers of growth including unmet
therapeutic needs, the rising incidence of
multiple diseases, ageing populations, the
rising living standards and fast-developing
geographical markets. The future of Lipitor
is therefore vitally important to Pfizer,
especially in this uncertain period of
economic changes and pressures.
This report includes detailed five-year
forecasts over the period 2008-2013, and NOW
features 10 and 15-year forecasts to help
you understand the medium-term prospects for
these markets.
This unique in-depth
management report examines the future
prospects for Lipitor from 2008-2023. It
delivers direct to you future sales
forecasts for leading Lipitor in all seven
major markets (7MM). This detailed report
highlights the most compelling must know
issues- Lipitor’s patent contention by
Pfizer in both 7MM and other markets in
order to block Ranbaxy’s immediate
penetration of generic Lipitor. In light of
healthcare drug bills increasing
exponentially, generic Lipitor will be
welcomed by managed care organisations (MCO)
and further widen the generic revenue
margins, visiongain concludes. This report
also tackles Lipitor’s significant
developments, potential opportunities on the
market and important contemporary matters,
especially commercial drivers and
restraints.
Unique benefits to you when you order this
report:
Primary research throughout: you will not
find this information anywhere else
Full searchable report when you buy the
company or corporate editions
Easily
downloadable copies of the report available
for offline reading
The report is filled with detailed charts,
analysis, figures, graphs and tables
1 Executive Summary
1.1 Lipitor Was the World's Best Selling
Drug In 2006
1.2 Lipitor Will Face Strong Competition
After Patent Expiration In Key Markets
1.3 Lipitor Is Embroiled In Patent
Challenges With Ranbaxy
2 Overview of Lipitor
(Atorvastatin)
2.1 Lipitor (Atorvastatin)
- The Cholesterol Reducing Drug
2.1.1 Pfizer Acquires Lipitor After Merging
With Warner-Lambert
2.1.2
Dyslipidemia
2.1.2.1 Classification
of Dyslipidaemia
2.1.3 Dyslipidaemia - a Major Risk Factor In
Developing Coronary Heart Disease In The
Western Population
2.1.4 Aetiology of Dyslipidaemia
2.1.4.1
Primary Causes of Dyslipidemia
2.1.4.2 Secondary
Causes of Dyslipidaemia
2.1.4.3 Diabetes A Leading Cause of
Secondary Dyslipidaemia
2.2 Obesity Is a Major Environmental Factor
Associated With Dyslipidaemia
2.2.1 Strong Link Between Diabetes And
Obesity
2.2.2 Diet
Remains An Important Component In Regulating
Lipid levels
2.2.3 Behaviour
2.2.4 Regular Physical Exercise
2.3 Symptoms and Signs of Dyslipidaemia
2.4 Diagnosis, Screening and Markers of
Dyslipidaemia
2.4.1 Direct
Measurement of Total cholesterol,
Triglycerides, And HDL
2.4.2 Estimation of
Low-density Lipoprotein (LDL) And Very
Low-Density Lipoprotein (VLDL)
2.4.3 Fasting Lipid Profile
2.4.4 Screening Patients Under 20 Years For
Atherosclerotic Risk Factors
2.4.5 Screening For Lipoprotein(a) levels
3 Treatment of Dyslipidaemia
3.1 Lipid Regulating Drugs Are Central
To Treating Dyslipidaemia
3.1.1 Statins are First Choice
Lipid-Regulating Drugs
3.1.2
Statin Drugs Are Significant Market for
Leading Pharmaceutical Companies
3.1.3 Lipitor A Second-Generation
3-hydroxy-3-methygulutaryl coenzyme A (HMGCoA)
Reductase Inhibitor Gold Standard Drug
3.2
Posology And Method of Administration of
Lipitor
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